ea0063p74 | Calcium and Bone 1 | ECE2019
Grebennikova Tatiana
, Slashchuk Konstantin
, Tarbaeva Natalia
, Rozhinskaya Liudmila
, Rodionova Svetlana
, Melnichenko Galina
, Rumjantsev Pavel
, Belaya Zhanna
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome of abnormal phosphate metabolism caused by a small mesenchymal tumor that secrete fibroblast growth factor 23 (FGF23). A 29-year-old female has suffered from two low-traumatic hip fractures, multiple fractures at the pelvic and sacrum, and diffuse bone pain for more than 3 years. Her mobility was limited in the last year (used crutches) because she had severe muscle weakness. Laboratory examination at the time ...